Tumor Environment & Metastasis Members
The Tumor Environment & Metastasis (TEAM) Program uses an integrative approach to elucidate key molecular interactions between tumor cells and components of the host stromal microenvironment including matrix, vascular structures and cells of the immune system.
Saleiro, Diana
Research Assistant Professor
Bio
Dr. Saleiro's goal is to identify novel targetable molecules within the interferon (IFN) pathways to enhance IFN-mediated anti-cancer effects. IFNs are considered potent cytokines with ... [more]
Satchell, Karla
Professor
Bio
My interest in the mechanisms of action of bacterial protein toxins spans over 27 years. I first started working on RTX toxins in 1988 as a research tech in pharmacology shortly after earning my under... [more]
Sosa-Pineda, Beatriz
Professor
Bio
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal forms of cancer, with a 5-year survival rate of less than 5%. In my lab we use mouse models of the disease and primary cultures from t... [more]
Sumagin, Ronen
Associate Professor
Bio
Studies in Dr. SumaginâÂÂs laboratory are focused on determining the contributions of immune cell-mediated inflammation to development and progression of colorectal cancers. Immune cells are critical ... [more]
Thorp, Edward
Professor
Bio
My laboratory examines the cell and molecular biology of inflammation and its resolution, which are key disease contributing factors in the tumor microenvironment. Although most of our in vivo tests p... [more]
Troyanovsky, Sergey
Professor
Bio
Dr. TroyanovskyâÂÂs research focuses on cadherin, intercellular, adhesion, and signaling. Classic cadherins are critical proteins mediating cell-cell adhesion and various signaling pathways responsib... [more]
Walsh, Derek
Professor
Bio
Research in our laboratory focuses on two aspects of DNA virus biology: 1) How poxviruses take control of host ribosomes and cell signaling pathways. 2) How herpesviruses, such as human... [more]
Wang, Chyung-Ru
Professor
Bio
My research focuses on the immune function of major histocompatibility complex (MHC) class Ib molecules in normal and diseased states. My lab is interested in understanding how MHC class Ib-restricted... [more]
Weinberg, Samuel
Assistant Professor
Bio
My group's research focuses on determining how cell-intrinsic and environmental metabolic alterations influence immune cell function and shape immunity, with the long-term goal of identifying cli... [more]
Wu, Jennifer
Professor
Bio
Research in my laboratory include these specific aspects: 1) mechanisms of cancer immune evasion; 2) development of novel cancer immunotherapy; 3) Immune therapy-related mucosal toxicity; 4) mechanism... [more]